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Reliable Source of Tris(hydroxymethyl)aminomethane Hydrochloride for Scientific and Industrial Use

Buffering agents are critical for controlling the stability of biochemical reactions, pharmaceutical formulations, and many analytical processes. Among the most widely trusted options is Tris(hydroxymethyl)aminomethane hydrochloride, also known as Tris HCl. With its ability to maintain a stable pH in biological and chemical systems, Tris HCl is regarded as a cornerstone material in laboratories and industrial production.
As a specialized biopharmaceutical manufacturer in China, we supply high-quality Tris HCl designed for global partners in research, healthcare, and applied chemistry. Our production capacity and strict quality controls ensure that customers receive a product that is consistent, reliable, and tailored to their specific needs.

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    PRODUCT DESCRIPTION

    Technical SpecificationsTechnical Specifications

    Parameter

    Specification / Details

    Chemical Name

    Tris(hydroxymethyl)aminomethane Hydrochloride (Tris-HCl)

    Chemical Formula

    C4H11NO3·HCl

    Appearance

    White crystalline powder

    Purity

    ≥ 99%

    pH (1% solution)

    4.0–5.5 (adjusted)

    Solubility

    Easily soluble in water; slightly soluble in ethanol

    Molecular Weight

    157.6 g/mol

    Melting Point

    171–174°C (decomposes)

    Packaging Options

    25 kg fiber drum / customized packaging available

    Applications

    - Buffer in biochemical and molecular biology research- pH stabilizer in enzyme reactions and nucleic acid studies- Used in electrophoresis and PCR buffers

    Industries

    - Biopharmaceutical laboratories- Molecular biology and research institutes- Diagnostic reagent manufacturers

    Advantages of Tris HClAdvantages of Tris HCl

     Wide buffering range (pH 7.0–9.0): Suitable for biological and chemical reactions.

     

     Stable and reliable: Ensures reproducibility in molecular biology protocols.

     

     Versatile applications: From healthcare to industrial chemistry.


     High safety profile: Low toxicity and suitable for pharmaceutical-grade use.

     

    Target Industries & Use CasesTarget Industries & Use Cases

    Biochemistry – buffer solution in protein and nucleic acid studies.

    Pharmaceutical research – pH control in formulations.

    Diagnostics – reagent in clinical laboratories.

    Cell culture – buffering agent in growth media.

    Molecular biology – electrophoresis buffer.

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    Application ScenariosApplication Scenarios

    🌍 Life Science Laboratories
    Tris HCl is one of the most frequently used buffering agents in DNA/RNA extraction, protein electrophoresis, and enzyme-based studies. Its stability helps researchers obtain reproducible and reliable results.

    ⚙️ Pharmaceutical Manufacturing
    Pharmaceutical companies utilize Tris HCl in drug formulations and vaccine production. As a buffer, it safeguards active pharmaceutical ingredients against degradation caused by pH fluctuations.

    🧠 Clinical Diagnostics
    Diagnostic kit manufacturers incorporate Tris HCl into test reagents to ensure consistent performance of assays. The compound provides reliable conditions for immunoassays and nucleic acid amplification techniques.

    🛠 Broader Industrial Applications
    Beyond biotechnology, Tris HCl is applied in electroplating, cosmetics, and specialty chemical processes, proving its adaptability across industries.

    Why Partner with Us?Why Partner with Us?

    Direct Factory Supply: Competitive pricing and consistent output.

     

    Strict QC Standards: Every batch undergoes comprehensive testing.

     

    Customized Solutions: Available in different purities and packaging sizes.

     

    Global Export Experience: Safe logistics and compliance with international requirements.

    Frequently Asked Questions (FAQ)FAQ

    • Q1: Why is Tris HCl more commonly used than Tris base in biological systems?

      A1: Tris HCl is pre-neutralized and easier to dissolve, eliminating the need for pH adjustment. This makes it more convenient for laboratories requiring ready-to-use buffers.
    • Q2: Can Tris HCl be used in large-scale pharmaceutical production?

    • Q3: How should Tris HCl be handled and stored?

    • Q4: Do you provide documentation such as Certificates of Analysis (COA) and MSDS?

    Production equipmentProduction equipment

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    Get a Quote or Technical ConsultationGet a Quote or Technical Consultation

    Tris(hydroxymethyl)aminomethane hydrochloride is more than a simple buffering compound—it is a trusted tool supporting critical advancements in science, medicine, and industry. By choosing a dependable manufacturer, laboratories and companies can secure the consistent supply and uncompromised quality that their projects demand.


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