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Tris(hydroxymethyl)aminomethane Hydrochloride:High-Purity Buffer for Research and Industrial Applications

Tris(hydroxymethyl)aminomethane hydrochloride, often abbreviated as Tris HCl, is a widely recognized buffering agent in both laboratory and industrial settings. With its strong ability to maintain stable pH values in biological and chemical systems, Tris HCl has become an indispensable material for research institutions, pharmaceutical manufacturers, and biotechnology companies. As a Chinese biopharmaceutical factory specializing in high-purity chemicals, we provide reliable Tris HCl tailored for global partners who demand consistency, safety, and performance.

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    PRODUCT DESCRIPTION

    Technical SpecificationsTechnical Specifications

    Parameter

    Specification / Details

    Chemical Name

    Tris(hydroxymethyl)aminomethane Hydrochloride (Tris-HCl)

    Chemical Formula

    C4H11NO3·HCl

    Appearance

    White crystalline powder

    Purity

    ≥ 99%

    pH (1% solution)

    4.0–5.5 (adjusted)

    Solubility

    Easily soluble in water; slightly soluble in ethanol

    Molecular Weight

    157.6 g/mol

    Melting Point

    171–174°C (decomposes)

    Packaging Options

    25 kg fiber drum / customized packaging available

    Applications

    - Buffer in biochemical and molecular biology research- pH stabilizer in enzyme reactions and nucleic acid studies- Used in electrophoresis and PCR buffers

    Industries

    - Biopharmaceutical laboratories- Molecular biology and research institutes- Diagnostic reagent manufacturers

    Key FeaturesKey Features

     Excellent pH buffering capacity in the range of 7.0–9.0
     High solubility and rapid dissolution in aqueous systems
    Low absorbance at UV wavelengths, suitable for protein and nucleic acid studies
     Consistent quality control in compliance with global standards

    Target Industries & Use CasesTarget Industries & Use Cases

    Biochemistry – buffer solution in protein and nucleic acid studies.

    Pharmaceutical research – pH control in formulations.

    Diagnostics – reagent in clinical laboratories.

    Cell culture – buffering agent in growth media.

    Molecular biology – electrophoresis buffer.

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    Application FieldsApplication Fields

    🌍1. Biotechnology and Life Sciences
    Tris HCl is frequently used to prepare buffer solutions for DNA and RNA extraction, protein purification, and enzyme reactions. Its stability ensures reliable results in sensitive molecular biology procedures.
    ⚙️2. Pharmaceutical Manufacturing
    In drug formulation and production, Tris HCl serves as an excipient and buffering component to maintain the stability of active pharmaceutical ingredients.
    🧠3. Diagnostics and Medical Devices
    Used in diagnostic reagents and test kits, it helps ensure consistent performance of assays where pH precision is crucial.
    🛠4. Industrial Chemistry
    Tris HCl also finds use in electroplating, cosmetics formulations, and other chemical processes requiring stable buffer systems.

    Why Choose Our Tris HCl?Why Choose Our Tris HCl?

    Factory Direct Supply: Competitive pricing with stable production capacity.
    Strict Quality Control: Every batch is tested to ensure purity and consistency.
    Flexible Supply Chain: We support bulk orders, OEM, and customized specifications.
    Global Shipping: Reliable packaging and logistics tailored for international clients.

    Frequently Asked Questions (FAQ)FAQ

    • Q1: What is the main difference between Tris base and Tris HCl?

      A1: Tris base is the unprotonated form, while Tris HCl is its hydrochloride salt. Tris HCl provides better solubility and is ready for use in buffer systems without additional neutralization steps.
    • Q2: Can Tris HCl be used in pharmaceutical formulations?

    • Q3: How should Tris HCl be stored to maintain stability?

    • Q4: Do you offer customized grades or smaller packaging for laboratory use?

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    Get a Quote or Technical ConsultationGet a Quote or Technical Consultation

    Tris(hydroxymethyl)aminomethane hydrochloride is more than just a buffering agent—it is a backbone material supporting countless laboratory protocols and industrial processes. By choosing a reliable manufacturer, research facilities and industries can ensure stable supply, consistent results, and long-term collaboration.


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